Boosting the Effects of a Particular MicroRNAs May Benefit Patients with Cervical Cancer

Dysregulation of microRNAs, which are molecules involved in controlling gene expression, can promote tumor formation and progression.
The FASEB Journal found that the miR-145 microRNA can suppress the growth of cervical cancer cells.
The FASEB Journal found that the miR-145 microRNA can suppress the growth of cervical cancer cells.Unsplash

Dysregulation of microRNAs, which are molecules involved in controlling gene expression, can promote tumor formation and progression. A study in The FASEB Journal found that the miR-145 microRNA can suppress the growth of cervical cancer cells.

miR-145 was expressed at lower than normal levels in human cervical cancer cells, and lower levels correlated with more advanced clinical stages of cervical cancer in patients. 

Cervical cancer is the fourth leading cause of cancer-related death in women worldwide.
Cervical cancer is the fourth leading cause of cancer-related death in women worldwide.Wikimedia Commons

Experiments in cells and mice revealed the mechanisms behind miR-145 effects and pointed to potential targets that could be manipulated to benefit patients with cervical cancer.

“Cervical cancer is the fourth leading cause of cancer-related death in women worldwide, and microRNA dysregulation plays an important role in its pathogenesis,” said co–corresponding author Kun Yang, PhD, of The Fourth Military Medical University, in China. “This study explored the potential mechanism of miR-145 in cervical cancer, suggesting that targeting miR-145 is expected to be an effective strategy for cervical cancer treatment.” (NS/Newswise)

Hurry up and join the Medical Internship 3.0!

The FASEB Journal found that the miR-145 microRNA can suppress the growth of cervical cancer cells.
No Safety Concerns Seen with Use of Dapivirine Vaginal Ring During Third Trimester of Pregnancy

Related Stories

No stories found.
logo
Medbound
www.medboundtimes.com