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Some cancers rely heavily on specific proteins to survive, revealing an exploitable weakness

Researchers map the activity of DNA repair proteins in individual cells, paving the way for advancements in cancer therapies

Learn the groundbreaking discoveries that could change the course of Huntington’s disease treatment

Saruparib is a new-generation oral inhibitor selectively targeting PARP1. The improved safety profile can allow for more combinations to bring benefits to patients in earlier disease stages.

Researchers have figured out how a specific metabolite controls the activity of DNA repair and how sensitive tissues are to cancer treatment

An experimental drug known as Yoda1 may help drain cranial waste plus neurotoxins that cause Alzheimer’s disease.