A recent study [1] published in the British Journal of Anesthesia highlighted the important association between accurate diagnosis of heart failure before major non-cardiac surgery, lower intraoperative fluid administration (primary outcome), and a reduced risk of postoperative acute kidney injury/AKI (secondary outcome) in adult patients.
The research was conducted in a single academic hospital involving patients undergoing major non-cardiac surgeries, for the span of 4 years from 2015 to 2019. The study employed diagnostic codes, keywords in the preoperative assessment and medical records, later reviewed by a multispecialty panel to confirm preoperative heart failure diagnosis.
The study revealed that patients accurately diagnosed with heart failure before non-cardiac surgery tend to require low intraoperative fluid (On average, < 470ml) and a reduction in the risk of postoperative AKI (adjusted odds ratio: 0.39) than those with undiagnosed heart failure.
False Negatives/True Positives: Patients with undiagnosed heart failure tends to have better left ventricular function and fewer comorbidities than those with an accurate diagnosis.
False Positives: Patients incorrectly diagnosed with heart failure were more likely to have lower ejection fractions, additional comorbidities, and were frequently undergoing thoracic surgeries.
The impact of accurate diagnosis of heart failure in adult patients influenced the intraoperative practice patterns and postoperative outcomes, beyond fluid management and AKI risk, which includes:
Reduced sedative use
Greater use of arterial line monitoring and inotropes
Postoperative lactate levels reached lower peak levels
Shorter hospital stays
Fewer Vasopressor Infusions
However, this study is observational, and a single-institution setting limits generalizability. Future research should explore broader populations and additional perioperative management strategies optimizing patient care.
References:
1. Deniau, Benjamin, Valentine Léopold, and Alexandre Mebazaa. "Accurate Diagnosis of Heart Failure and Improved Perioperative Outcomes." British Journal of Anaesthesia 134, no. 1 (January 2025): 1–4. https://doi.org/10.1016/j.bja.2024.10.003.
(Input from various media sources)
(Rehash/Dr. Disha Merlyn Mathias/SSK)