At NASA, pharmacists mainly focus on preparing “convenience” and “contingency” medical kits for astronauts at the International Space Station. Photo by NASA Hubble Space Telescope on Unsplash
Pharmacy

Prescribing from the Stars: The Promise of Astropharmacy

Astropharmacy, a branch of space medicine, focuses on the development, production, storage, and use of medications in space

Dr. Rametrika Saha

In the vast expanse of the cosmos, where stars twinkle and the galaxies sway, a new horizon in healthcare is emerging – Astromedicine and Astropharmacy. This innovative field delves into the potential of space-derived elements to revolutionize our approach to health and wellness.

Disease is an inherent part of being alive, which makes it crucial to focus on preventing, diagnosing and treating illnesses for human activities in outer space. Pharmaceuticals play a crucial role in diagnosing, treating, curing or preventing diseases; however, they encounter challenges in maintaining stability both on Earth and especially in space. Imagine if small amounts of pharmaceuticals could be produced on-site in space on demand. Biopharmaceuticals, also known as biologics (which include peptide or protein drugs), would be particularly suitable for manufacturing in space. Many medical conditions and emergencies that astronauts are likely to encounter can be effectively treated with these types of medications. [1]

Astropharmacy also investigates how space travel impacts the human body and how drugs function differently in microgravity and environments with high radiation.

MedBound Times, connected with Professor Phil Williams, a key voice in the emerging field of Astropharmacy at the University of Nottingham, Nottingham, England. Sharing his perspective, Professor Williams stated:

Spaceflight pushes the limits of human biology. To ensure safe and effective healthcare for astronauts, we need to rethink everything we know about medicines—from how they’re made, to how they work inside the body.
Professor Phil Williams, Founder of Astropharmacy at University of Nottingham

The difficulties of providing pharmaceutical support become even more complex when we take into account the nutritional requirements of astronauts and future colonists. During space travel, the human body undergoes various changes due to microgravity, including muscle atrophy, fluid redistribution, changes in the microbiome, bone decalcification, and alterations in gut enzymes.

Among the most pressing risks astronauts may face are:

  •  Haematological crises (stroke, myocardial infarction, pulmonary embolisms, etc.)

  •  Bacterial challenges resulting from either changes in their microbiome or the introduction of foreign bacteria.

Bacteria are becoming increasingly resistant to antibiotics, making these medications less effective. Additionally, the immune system can weaken, which means our brave explorers may require significant medical attention, creating yet another challenge.

During space travel, the processes of pharmacokinetics and pharmacodynamics can vary, necessitating customized medications that are available exactly when needed. However, we cannot bring every possible medication with us, so we must explore methods to produce pharmaceuticals in situ and on demand. [2]

While a small proportion of pharmacists are actively involved with space participant health in the space sector, their role has much more potential, being primarily centred around medication utilisation reviews for astronauts at the ISS.

The University of Nottingham (UK), provides a unique elective module titled Astropharmacy & Astromedicine (PHAR3026). This course is specifically designed for third-year students studying Pharmacy or Pharmaceutical Sciences (BSc/MSci). [1]

Astromedicine and astropharmacy go beyond simply drawing inspiration from the stars; they focus on utilizing the unique properties of cosmic materials for therapeutic purposes. The universe is filled with potential remedies waiting to be discovered and used for their healing benefits. Astromedicine explores the extraction of medicinal compounds from celestial bodies, aiming to create elixirs that could improve human longevity, strengthen immunity and even encourage tissue regeneration. While these ideas remain largely theoretical, they highlight the immense potential of pharmaceuticals in space and space pharmacy research. The pursuit of these cosmic remedies holds the promise of a future where healthcare is not only effective but also inspired by the marvels of the universe.

As we gaze into the cosmos, we discover not only a source of inspiration but also immense possibilities for improving healthcare. Astromedicine and astropharmacy encourage us to think beyond Earth and consider the role of pharmaceuticals in space, drug stability in microgravity, and broader space medicine. This journey is just beginning, and with each discovery, we move closer to a future where the stars may play a crucial role in our health. Embrace the era of cosmic remedies, where the universe serves as the ultimate pharmacist and healer.

"Ad aspera ad astra!" (Through hardship to the stars)

References:

1. University of Nottingham. Astropharmacy and Astromedicine. Retrieved August 26, 2025, from University of Nottingham School of Pharmacy website: https://www.nottingham.ac.uk/pharmacy/research/molecular-therapeutics-and-formulation/research/astropharmacy-and-astromedicine.aspx

2. Aziz S, Raza MA, Noreen M, Iqbal MZ, Raza SM. Astropharmacy: Roles of Pharmacist in Space. Innov Pharm. 2022 Dec 12;13(3):10.24926/iip.v13i3.4956. doi: 10.24926/iip.v13i3.4956. PMID: 36627911; PMCID: PMC9815863.

Reviewed by Dr. Shikhar Dabas

MSM

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