Deep brain-machine interfaces - interacting with Human deep brain

A new level of human interaction with technology and the environment is provided through Brain-Machine Interface
Major electrical recording and stimulation approaches for brain machine interfaces.
Major electrical recording and stimulation approaches for brain machine interfaces.Newswise

Brain-Machine Interface (BMI, also known as Brain-Computer Interface) provides a new dimension for a human to interact with machines and the environment. Brain-machine interfaces help restore or improve human physical or mental functions. Scientists investigate a variety of technologies to interact with the brain at different levels.

The cerebral cortex has long been the research target of the brain-machine interface. By recording neural activity in multiple cortical regions to understand human intent, researchers enable paralyzed patients to control robotic arms and prosthetics and help disabled people communicate effectively.

Conventional brain-computer interfaces allow us to decode sensory and motor signals such as visual responses, hand movements, and speech in a constrained lab environment. It is still challenging to apply these technologies to everyday life.

Common approaches for sensing and modulating human brain.
Common approaches for sensing and modulating human brain.Newswise

Deep brain regions are heavily involved in basic life functions. It is necessary to investigate deep brain functions to achieve a better understanding of how the brain works. Subcortical brain regions are the main targets for invasive neuromodulation and clinical neurotherapy. Structural and functional abnormalities of the human deep brain are observed in a variety of neurological and psychiatric disorders, including Parkinson's disease, Alzheimer's disease, depression, and obsessive-compulsive disorder, etc. Deep brain-machine interfaces focus on understanding and modulating neural activities in deep brain regions. It is an emerging research field with great potential for clinical applications.

Sensing and modulation via deep brain machine interface.
Sensing and modulation via deep brain machine interface.Newswise

The above figure illustrates major methods for recording and stimulation ranging from the surface to the deep brain. In addition to recording and decoding, deep brain-machine interfaces are also able to modulate pathological states of the brain by delivering therapeutic stimuli. Advanced DBMI technology is designed to record and decode deep neural activity with high spatiotemporal resolution and efficiently configure stimulation parameters for precise modulation of brain states. Developing DBMI with long-term efficacy remains challenging due to our limited understanding of the mechanisms including plasticity and adaptations of the central nervous system.

Major electrical recording and stimulation approaches for brain machine interfaces.
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Since the nervous system mainly transmits information through electrical signals, brain-computer interfaces mediated by electrical signals have attracted the most research interest in this field. The article outlines the current neural electrical activity-based brain-computer interface technologies available for humans and their applications in sensing and modulating brain activity. The authors introduce two widely used deep brain interface systems, deep brain stimulation (DBS) and stereotactic electroencephalography (sEEG), with special attention to the latest technological advances and clinical applications. The potential of DBMI to be used as a powerful brain research platform and its therapeutic utility are addressed. The paper also discusses the closed-loop control framework of DBMI systems and the development of closed-loop deep-brain interface technology for clinical applications. (NJ/Newswise)

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Major electrical recording and stimulation approaches for brain machine interfaces.
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