

Have you ever thought about mixing different cleaners to make a stronger one? Here’s the catch: mixing cleaning chemicals can be extremely dangerous.
One such incident was shared by pulmonologist Dr. Ankit Bhatia (MBBS, MD Pulmonology, IDCCM, EDRM, FAPSR), who recently encountered a case that serves as a stark reminder of the hidden dangers lurking in our household cleaning cabinets.
A patient was brought to the emergency department gasping for breath after a routine bathroom cleaning session went horribly wrong.
The incident occurred when she mixed two popular toilet cleaners: red Harpic and blue Harpic. Within minutes, toxic fumes filled the bathroom. She developed sudden breathlessness, collapsed, and had to be rushed to the hospital.
The deadly potential of this combination lies in basic chemistry. The main constituents of the Red and Blue Harpic react with each other. Ingredients are as follows:
Red Harpic contains sodium hypochlorite (0.5% w/w), commonly known as bleach, which is used to whiten clothes and disinfect surfaces.
Blue Harpic contains hydrochloric acid (10.5% w/v), a strong corrosive acid used to remove tough stains and mineral deposits.
When these two substances mix, a dangerous chemical reaction occurs: chlorine gas is released, which is highly toxic and can cause immediate, severe damage to the respiratory system.
Gaseous chlorine is a pulmonary irritant. Exposure can lead to:
Burning sensations in the eyes, throat, and bronchial tree
Coughing, wheezing, and shortness of breath
Severe cases may cause bronchospasm, pulmonary injury, and delayed pulmonary edema 1
Dr. Bhatia’s patient developed Reactive Airways Dysfunction Syndrome (RADS), a condition where asthma-like symptoms appear suddenly after exposure to toxic gases and can persist long after the initial incident.
RADS is characterized by the sudden onset of airway reactivity following acute exposure to an irritant gas or vapor.
A landmark study by researchers Metin Gorguner, Sahin Aslan, Tacettin Inandi, and Zeynep Cakir examined 55 patients who presented to emergency departments after inhaling fumes from a bleach-hydrochloric acid mixture. Their finding was alarming ,"64% of exposures occurred in bathrooms or kitchens, the most common areas for cleaning accidents."2
"One wrong combination can permanently damage your lungs," warns Dr. Bhatia. The damage from chlorine gas exposure isn’t always reversible. Some patients continue to experience breathing difficulties, reduced lung capacity, and asthma-like symptoms months or even years after the initial incident.
The Golden Rule: Never Mix Cleaning Products: The solution is simple but critical: always use only one cleaner at a time.
Dr. Ankit Bhatia's Essential Safety Guidelines:
Never mix Harpic with bleach, acids, or other cleaners.
Use only ONE product at a time.
Always ventilate your washroom.
References:
1. Morim A, Guldner GT. Chlorine Gas Toxicity. [Updated 2023 Jun 26]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK537213/
2. Gorguner M, Aslan S, Inandi T, Cakir Z. Reactive airways dysfunction syndrome in housewives due to a bleach-hydrochloric acid mixture. Inhal Toxicol. 2004 Feb;16(2):87-91. doi: 10.1080/08958370490265004. PMID: 15204781.