PCOS Is More Than Irregular Periods: Experts Unpack the Hormone–Mood Link

Experts highlight how hormonal imbalances in PCOS contribute to anxiety, depression, and body image struggles.
A poster for PCOS, showing an animated picture of a uterus, an ovary with multiple cysts, a sad female with acne and another sad girl.
Polycystic ovary syndrome (PCOS) is a common hormonal condition that affects women of reproductive age.AI generated
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September is marked as the PCOS Awareness Month.

According to World Health Organization (WHO) , Polycystic ovary syndrome (PCOS) is a common hormonal condition that affects women of reproductive age. It usually starts during adolescence, but symptoms may fluctuate over time. 1

MedBound Times connected with a few experts to discuss the physical, psychological, and social implications of PCOS on women’s health.

Dr. Sudipta Banerjee Oberoi, MRCOG DNB, Consultant Obstetrician and Gynaecologist, NHS, UK. explains the major symptoms that gynecologists look to confirm positive diagnosis for PCOS.

You should look for a few things: one will be irregular periods or weight gain and overgrowth of facial hair. These are the clinical features. Along with that you can use blood tests, that tell you that if the lady is not ovulating resulting in irregular periods. Then if the ultrasound is suggestive of multiple follicles in both the ovaries (from where the name comes) then you can confirm the diagnosis.
Dr. Sudipta Banerjee Oberoi, MRCOG DNB, Consultant Obstetrician and Gynaecologist, NHS, UK

Dr. Prarthna, MBBS-LHMC, MD Pathology, Senior resident at University College of Medical Science and Guru Teg Bahadur Hospital says:

"As a healthcare professional, I've seen the firsthand distress that PCOS can cause. The symptoms are multifaceted – irregular periods, excess hair growth, acne, and ovarian cysts. But it's not just the physical symptoms that are challenging; the emotional toll of PCOS can be just as significant."

She also commented on the implications that women go through beyond irregular periods.

"The impact on reproductive health is profound. Women with PCOS may experience difficulty conceiving, and if they do become pregnant, they're at a higher risk of complications like gestational diabetes and preeclampsia."

Dr. Prarthna, MBBS-LHMC, MD Pathology, Senior resident at UCMS and GTBH

An illustration of the female reproductive tract showing one normal ovary and the other with multiple cysts.
PCOS can cause anxiety, depression and mood swings.BruceBlaus/ Wikimedia commons

How Society Shapes the Psychological Struggles of Women with PCOS

Liza Hazarika, Psychologist (MA Clinical Psychology), spoke to MedBound Times about the body image issues and stigma related to PCOS.

"In our society we hold different kind of beauty standards, right? A clear skin and a certain kind of body shape, hair growth or just hair on body is considered unhygienic which is again not at all, it's completely the different, the opposite actually."

"So, some women with PCOS can have a lot of body image issues because of the physiological changes, because of weight, pimples or excessive hair on their body."

Liza commented that some women with PCOS also consider themselves less confident because of the insecurities related to their bodies.

"They can experience constant mood swings. They may feel sad, low, anxious, nervous, or even hyperactive. So, there are difficulties in their lifestyle, in their mood," she added.

PCOS should not be a Taboo

Experts agree that awareness is key. Women need to be educated about the symptoms of PCOS, the risks of untreated hormonal imbalance, and available treatment options.

We need to encourage women to seek professional help if they're experiencing symptoms. We also need to provide support and resources for women with PCOS.
Dr. Prarthna, MBBS-LHMC, MD PATHOLOGY-UCMS and GTBH.

All the experts stressed about working together as a society, to make a difference in the lives of women with PCOS.

"Let's prioritize the health and well-being of women with PCOS. Let's provide them with the care and support they deserve," Dr. Prarthna added.

Reference

1. World Health Organization. “Polycystic Ovary Syndrome.” Newsroom Fact Sheets, February 7, 2025. Accessed September 8, 2025. WHO.
https://www.who.int/news-room/fact-sheets/detail/polycystic-ovary-syndrome

Reviewed by Dr Sumbul

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