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What is HDL (High Density Lipoprotein)?
HDL-C (High Density Lipoprotein Cholesterol) is commonly known as “good cholesterol” because it can lower the risk of developing heart disease and stroke.
What is Glaucoma?
Glaucoma is a chronic eye illness that destroys the optic nerve and causes vision loss, according to the World Health Organisation (WHO). This set of eye conditions has the potential to result in blindness.[1]
New study carried out by British Journal of Ophthalmology revealed an astonishing result with respect to different serum lipids and glaucoma.
This study was one of a kind as it involved 4,00,229 candidates from UK Biobank and it was the first time LDL-C (Low-Density Lipoprotein Cholesterol), HDL-C (High-Density Lipoprotein Cholesterol), Triglycerides (TG) and Total Cholesterol (TC) were assessed with respect to glaucoma.[2]
Traditionally, HDL-C is associated with good cardiovascular health as it can prevent formation of cholesterol plaque in arteries, carry cholesterol to the liver and absorb blood cholesterol. However, the definition of “good” cholesterol is inverse in relation to eye health.
Whole blood analysis was done and serum-lipid concentrations were analyzed. Genetic examination was also carried out to assess the relations between glaucoma and serum lipid.
RESULTS:
Greater levels of "good" HDL cholesterol were linked to an increased risk of glaucoma, whereas greater levels of "bad" LDL cholesterol, total cholesterol, and triglycerides were linked to a decreased risk, according to an analysis of the blood test findings.
CONCLUSION:
The research study demonstrated that candidates 55 years of age who had higher levels of High-Density Lipoprotein Cholesterol (HDL-C) were associated with elevated risks of developing glaucoma.
REFERENCES:
[1] “World Health Organization (WHO).” n.d. Who.int. Accessed February 11, 2025. https://www.who.int/.
[2] Ma, Yiyuan, Yue Wu, Leyi Hu, Wen Chen, Xinyu Zhang, Danying Zheng, Nathan Congdon, Guangming Jin, and Zhenzhen Liu. 2025. “Associations between Serum Lipids and Glaucoma: A Cohort Study of 400 229 UK Biobank Participants.” The British Journal of Ophthalmology, bjo-2024-326062. https://doi.org/10.1136/bjo-2024-326062.
(Input from various sources)
(Rehash/Sanika Dongre/MSM)
