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Exhausted T cells exhibit mitochondrial dysfunction, accompanied by diminished mitochondrial mass and polarized mitochondria, and elevated ROS production.

Structural insights from cryo-electron microscopy could lead to drugs that target midnolin in leukemias, lymphomas, and multiple myelomas

New research uncovers strategies to eliminate sleeping breast cancer cells before they reignite disease.

Scientists explore how disrupting cell migration could transform cancer treatment

CAR-T cells produced from the T cells of aged mice tend to lack “stemness”—the capacity to expand rapidly and efficiently kill their cellular targets.

In certain cancers, QRICH1 could be used to increase T-cell activation to fight and kill off cancer cells more effectively